VRG Therapeutics (VRGTx) (VRG Therapeutics) is a pioneering biopharmaceutical R&D company headquartered in Budapest, Hungary. VRG Tx has a continuously growing R&D portfolio focused on innovative miniprotein-peptide based pharmaceuticals and Cell and Gene Therapy (CGT) research programs. We are building a world-class AI-driven drug discovery platform with a singular mission: to cure diseases by targeting biological mechanisms that are inaccessible to traditional therapeutic approaches. Our discovery engine integrates machine learning, physics-based modeling, and experimental validation to design novel protein therapeutics.
Role Overview
Perform and document laboratory-scale peptide,miniprotein and recombinant protein preparation workflows, including sample preparation, purification, polishing and formulation-supporting activities
Operate and help optimize preparative chromatography and protein/peptide analytical methods such as ÄKTA/FPLC,RP/SEC/IEX/HIC/affinity chromatography, HPLC/UPLC-based assays and LC-MS-supporting workflows.
Support recombinant expression and purification workflows in prokaryotic and/or eukaryotic systems, including small-scale expression testing and process troubleshooting.
Maintain accurate experimental records, raw data files, protocols, sample/batch documentation and technical reports in a traceable format.
Review scientific literature, integrate experimental data and contribute practical solution options to project teams.
Apply modern data-analysis approaches where relevant, including AI-assisted analysis, sequencing/NGS-derived datasets and big-datae valuation
Required Qualifications
MSc or PhD degree in biochemistry,biotechnology, molecular biology, pharmaceutical sciences, chemistry, chemical egineering, bioengineering or a related biomedical/natural science discipline.
Hands-on laboratory experience in an academic or industry research environment; protein/peptide work,purification or analytical characterization
Practical understanding of chromatography-based purification and analytical characterization of proteins, peptides or other biologics
Recombinant protein expression in E. coli, mammalian, yeast or insect systems; inclusion-body processing/refolding is an advantage
Gene design, cloning, expression-plasmid construction or gene-editing workflows supporting recombinant protein production
NGS/sequencing data evaluation, AI-supported scientific workflows or big-data analysis
Peptide/miniprotein chemistry, oxidative folding, lyophilization, binding assays or functional potency assays knowledge is an advantage.
Personal Attributes
Ability to work independently, recognize technical problems and clear result communication
Strong documentation discipline, sample tracking and raw-data handling
Precision,reliability and ownership in laboratory work, documentation and data interpretation.
Result-oriented, flexibility and proactive problem-solving mindset with ability to adopt new technologies
Strong interpersonal skills that support effective work across a multidisciplinary team
Development Opportunities
The opportunity to work on best-in-class and first-in-class therapeutic concepts
A highly collaborative, science-driven international culture with strong academic and industry roots
Competitive compensation aligned with experience
Professional growth in biologics R&D, protein analytics, recombinant protein production and preparative purification.
Opportunity to build an individual scientific career path, including PhD studies for MSc-level candidates or PhD-level research ownership as aligned with the candidate and company goals.
LOCATION
Budapest, Hungary
JOB TYPE
full-time
SALARY
Commensurate with role and experience
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If you are interested in this position, please upload your CV and motivation letter to our Careers page.
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